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LSD has two labile protons for the tertiary stereogenic C5 and C8 positions, rendering these facilities susceptible to epimerisation. The C8 proton is a lot more labile mainly because of the electron-withdrawing carboxamide attachment, but removing of the chiral proton within the C5 posture (which was when also an alpha proton from the parent molecule tryptophan) is assisted with the inductively withdrawing nitrogen and pi electron delocalisation With all the indole ring.[citation needed]

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As a gaggle, impartial producers are of less problem into the Drug Enforcement Administration than the large-scale teams simply because their product reaches only community markets.[173]

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